Associação entre vitamina D, controle glicêmico e complicações microvasculares no diabetes tipo 1

Camila Lousada Herbster Ferraz, Angela Delmira Nunes Mendes, Tania Maria Bulcão Lousada Ferraz, Carlos Antonio Bruno da Silva

Resumo


Objetivo: Avaliar a associação entre os níveis de vitamina D, os parâmetros do controle metabólico e a presença de complicações microvasculares em pacientes portadores de diabetes mellitus tipo1 (T1DM). Métodos: Estudo transversal, analítico e observacional, realizado em 2016, em Fortaleza, Ceará, com prontuários de cinquenta pacientes. Investigaram-se os dados clínicos e epidemiológicos: sexo, idade, IMC (índice de massa corporal), cor da pele, controle glicêmico, duração do diabetes, dose diária de insulina, presença de complicações microvasculares e dosagem de vitamina D por quimiluminescência. Utilizaram-se os testes exato de Fisher, t-Student e Mann-Whitney com p< 0,05. Resultados: Observou-se deficiência de vitamina D em 34 (68%) pacientes, com média de 25(OH) de vitamina D, 23,24 ± 4,29 ng/mL no grupo vitamina D deficiente e 38,22± 7,72 ng/mL no grupo vitamina D suficiente. Além disso, 37 pacientes (78%) apresentaram hemoglobina glicada acima de 7% e semelhante nos dois grupos. A dose diária de insulina no grupo vitamina D deficiente foi maior que no grupo vitamina D suficiente, 54,81 + 27,4 vs 55,55 + 19,2, mas sem associação significativa com níveis de vitamina D. O nível sérico da vitamina D não se associou com parâmetros clínicos e epidemiológicos, como: sexo, idade, IMC, cor da pele, controle glicêmico, duração do diabetes, dose diária de insulina e presença de complicações microvasculares. Conclusão: A deficiência de vitamina D esteve presente na maioria dos pacientes com T1DM avaliados. No entanto, sem associação entre essa deficiência e as variáves clínicas e epidemiológicas analisadas.

Palavras-chave


Diabetes Mellitus; Vitamina D; Registros Médicos.

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DOI: http://dx.doi.org/10.5020/18061230.2018.6993

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Licença Creative Commons
Esta obra está licenciada sob uma licença Creative Commons Atribuição 4.0 Internacional.

Licença Creative Commons
Esta obra está licenciada com uma Licença Creative Commons Atribuição 4.0 Internacional.
Rev Bras Promoç Saúde, Fortaleza - Ceará - Brasil - e-ISSN: 1806-1230

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