Associação entre osteoartrite de joelho e síndrome metabólica: uma revisão sistemática

Maura Fernandes Franco, Daniel Vicentini De Oliveira, Arlete Maria Valente Coimbra

Resumo


Objetivo: Identificar as possíveis associações entre osteoartrite de joelho (OA) e síndrome metabólica (SM). Métodos: Revisão sistemática de literatura, ocorrida entre os anos de 2012 e 2017, nas bases: Biblioteca Virtual em Saúde (BVS), SciELO, Cochrane e Embase; em português e/ou inglês, com os descritores “osteoartrite” e “síndrome metabólica” em ambas as línguas. Para avaliação da qualidade metodológica, utilizou-se a Declaração STROBE (Strengthening the Reporting of Observational Studies in Epidemiology). Selecionaram-se sete artigos, todos com qualidade metodológica alta. Resultados: Os dados apontam para associação entre OA sintomática e hipertensão arterial sistêmica, dislipidemia e o número de fatores acumulados, com aumento da gravidade e progressão dos sintomas em mulheres. Entretanto, ainda não se esclareceu por completo a associação entre o estado pré-inflamatório da SM e a OA. Conclusão: Os resultados encontrados sugerem que uma melhor compreensão das ações das vias metabólicas envolvidas com a osteoartrite de joelho poderia abrir uma nova avenida terapêutica a esses pacientes.

Palavras-chave


Osteoartrite; Síndrome Metabólica; Obesidade; Hipertensão

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Referências


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DOI: http://dx.doi.org/10.5020/18061230.2019.8448

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Esta obra está licenciada sob uma licença Creative Commons Atribuição 4.0 Internacional.

Licença Creative Commons
Esta obra está licenciada com uma Licença Creative Commons Atribuição 4.0 Internacional.
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